Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50205283
Substrate
n/a
Meas. Tech.
ChEMBL_425911 (CHEMBL907971)
Ki
637±n/a nM
Citation
 Chang, LC; von Frijtag Drabbe Künzel, JK; Mulder-Krieger, T; Westerhout, J; Spangenberg, T; Brussee, J; Ijzerman, AP 2,6,8-trisubstituted 1-deazapurines as adenosine receptor antagonists. J Med Chem 50:828-34 (2007) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50205283
Synonyms:
2,6-diphenyl-8-cyclohexyl-1-deazapurine | CHEMBL219160 | LUF-5981
Type:
Small organic molecule
Emp. Form.:
C24H23N3
Mol. Mass.:
353.4595
SMILES:
C1CCC(CC1)c1nc2c(cc(nc2[nH]1)-c1ccccc1)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: