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Target
cGMP-dependent protein kinase
Ligand
BDBM50211820
Substrate
n/a
Meas. Tech.
ChEMBL_447195 (CHEMBL897494)
IC50
0.1±n/a nM
Citation
 Liang, GB; Qian, X; Feng, D; Fisher, M; Brown, CM; Gurnett, A; Leavitt, PS; Liberator, PA; Misura, AS; Tamas, T; Schmatz, DM; Wyvratt, M; Biftu, T Synthesis and SAR studies of potent imidazopyridine anticoccidial agents. Bioorg Med Chem Lett 17:3558-61 (2007) [PubMed]  Article 
Target
Name:
cGMP-dependent protein kinase
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
112911.27
Organism:
Eimeria tenella
Description:
ChEMBL_469577
Residue:
1003
Sequence:
MGACSSKAQHQTRDPEPREQQAAQEQKSTGPSGAPNDAPAPAEAERKMSGSSATAPKGEMPTASTGTPEQQQQQQQQQQQQQEQQQHPEHQQSEKQQQHGEEQQQERKPSQQQQNEEAAAPHKHGGERKVQKAIKQQEDTQAEDARLLGHLEKREKTPSDLSLIRDSLSTNLVCSSLNDAEVEALANAVEFFTFKKGDVVTKQGESGSYFFIVHSGEFEVIVNDKVVNKILTGQAFGEISLIHNSARTATIKTLSEDAALWGVQRQVFRETLKQLSSRNFAENRQFLASVKFFEMLTEAQKNVITNALVVQSFQPGQAIVKEGEKGDVLYILKSGKALVSIKNKEVRVLQRGEYFGERALLYDEPRSATITAEEPTVCVSIGRDLLDRVLGNLQHVLFRNIMLEALQQSKVFASFPTEQLSRLIGSVVVKDYPENYIILDRENRTRASASALFSAQGVRFFFVLEGEVSVFAYKDKSSSSSSSSSSSSSSSSAEGEMELHLIDTLKRGQAFGDEYVLSPNKPFAHCVKSNGPTKLALLTASALTATLGGQDIDETLDYNNKLAITKKMYIFRYLSEQQTQTLIKAFKTVRYTQGESIIREGEIGSRFFIIKLGEVVILKGEKRVRTLGRHDYFGERALLHDERRSATVAANSPEVDLWVVDKDVFLQIVKGPMLTHLEERIRMQDTKVEFKDLNVVRVVGRGTFGTVKLVQHIPTQMRYALKCVSRKSVVALNQQDHIRLEREIMAENDHPFIIRLVRTFRDKEFLYFLTELVTGGELYDAIRKLGLLGRYQAQFYLASIVLAIEYLHERNIAYRDLKPENILLDSQGYVKLIDFGCAKKMQGRAYTLVGTPHYMAPEVILGKGYTLTADTWAFGVCLYEFMCGPLPFGNDAEDQLEIFRDILAGKLIFPHYVTDQDAINLMKRLLCRLPEVRIGCSINGYKDIKEHAFFSDFDWDRLAGRDLSPPLLPKGEIYAEDAEEGGLDIEEDEGIELEDEYEWDKDF
  
Inhibitor
Name:
BDBM50211820
Synonyms:
4-(7-(((2-(azetidin-1-yl)ethyl)(methyl)amino)methyl)-2-(4-fluorophenyl)H-imidazo[1,2-a]pyridin-3-yl)-N-((S)-1-phenylethyl)pyrimidin-2-amine | CHEMBL234059
Type:
Small organic molecule
Emp. Form.:
C32H34FN7
Mol. Mass.:
535.6577
SMILES:
C[C@H](Nc1nccc(n1)-c1c(nc2cc(CN(C)CCN3CCC3)ccn12)-c1ccc(F)cc1)c1ccccc1
Structure:
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