Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50215109
Substrate
n/a
Meas. Tech.
ChEMBL_448186 (CHEMBL898446)
EC50
>100000±n/a nM
Citation
 Ravn, J; Qvortrup, K; Rosenbohm, C; Koch, T Design, synthesis, and biological evaluation of LNA nucleosides as adenosine A3 receptor ligands. Bioorg Med Chem 15:5440-7 (2007) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50215109
Synonyms:
(1R,3R,4R,7S)-(7-hydroxy-3-(adenin-9-yl)-2-oxa-5-azabicyclo[2:2:1]hept-1-yl)-N-methylcarboxamide | CHEMBL391279
Type:
Small organic molecule
Emp. Form.:
C12H15N7O3
Mol. Mass.:
305.2926
SMILES:
CNC(=O)[C@]12CN[C@H]([C@@H]1O)[C@@H](O2)n1cnc2c(N)ncnc12
Structure:
Search PDB for entries with ligand similarity: