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Target
Cannabinoid receptor 1
Ligand
BDBM50218270
Substrate
n/a
Meas. Tech.
ChEMBL_448729 (CHEMBL897875)
IC50
1700±n/a nM
Citation
 Ohta, H; Ishizaka, T; Yoshinaga, M; Morita, A; Tomishima, Y; Toda, Y; Saito, S Sulfonamide derivatives as new potent and selective CB2 cannabinoid receptor agonists. Bioorg Med Chem Lett 17:5133-5 (2007) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50218270
Synonyms:
(Z)-N-(5-tert-butyl-3-(cyclopropylmethyl)-4-methylthiazol-2(3H)-ylidene)naphthalene-1-sulfonamide | CHEMBL236374
Type:
Small organic molecule
Emp. Form.:
C22H26N2O2S2
Mol. Mass.:
414.584
SMILES:
Cc1c(s\c(=N/S(=O)(=O)c2cccc3ccccc23)n1CC1CC1)C(C)(C)C
Structure:
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