Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50218275
Substrate
n/a
Meas. Tech.
ChEMBL_448728 (CHEMBL897874)
IC50
490±n/a nM
Citation
 Ohta, H; Ishizaka, T; Yoshinaga, M; Morita, A; Tomishima, Y; Toda, Y; Saito, S Sulfonamide derivatives as new potent and selective CB2 cannabinoid receptor agonists. Bioorg Med Chem Lett 17:5133-5 (2007) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50218275
Synonyms:
(Z)-N-(5-tert-butyl-3-(cyclopropylmethyl)-4-methylthiazol-2(3H)-ylidene)naphthalene-2-sulfonamide | CHEMBL393620
Type:
Small organic molecule
Emp. Form.:
C22H26N2O2S2
Mol. Mass.:
414.584
SMILES:
Cc1c(s\c(=N/S(=O)(=O)c2ccc3ccccc3c2)n1CC1CC1)C(C)(C)C
Structure:
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