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Target
Serotonin N-acetyltransferase
Ligand
BDBM50224326
Substrate
n/a
Meas. Tech.
ChEMBL_450671 (CHEMBL900954)
IC50
402000±n/a nM
Citation
 Szewczuk, LM; Saldanha, SA; Ganguly, S; Bowers, EM; Javoroncov, M; Karanam, B; Culhane, JC; Holbert, MA; Klein, DC; Abagyan, R; Cole, PA De novo discovery of serotonin N-acetyltransferase inhibitors. J Med Chem 50:5330-8 (2007) [PubMed]  Article 
Target
Name:
Serotonin N-acetyltransferase
Synonyms:
AANAT | SNAT | SNAT_SHEEP
Type:
PROTEIN
Mol. Mass.:
23086.34
Organism:
Ovis aries
Description:
ChEMBL_450671
Residue:
207
Sequence:
MSTPSVHCLKPSPLHLPSGIPGSPGRQRRHTLPANEFRCLTPEDAAGVFEIEREAFISVSGNCPLNLDEVQHFLTLCPELSLGWFVEGRLVAFIIGSLWDEERLTQESLALHRPRGHSAHLHALAVHRSFRQQGKGSVLLWRYLHHVGAQPAVRRAVLMCEDALVPFYQRFGFHPAGPCAIVVGSLTFTEMHCSLRGHAALRRNSDR
  
Inhibitor
Name:
BDBM50224326
Synonyms:
CHEMBL440979 | {4-[(4-benzyloxy-benzoyl)-hydrazonomethyl]-phenoxy}-acetic acid
Type:
Small organic molecule
Emp. Form.:
C23H20N2O5
Mol. Mass.:
404.4153
SMILES:
OC(=O)COc1ccc(\C=N\NC(=O)c2ccc(OCc3ccccc3)cc2)cc1
Structure:
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