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Target
Serotonin N-acetyltransferase
Ligand
BDBM50224328
Substrate
n/a
Meas. Tech.
ChEMBL_450671 (CHEMBL900954)
IC50
52900±n/a nM
Citation
 Szewczuk, LM; Saldanha, SA; Ganguly, S; Bowers, EM; Javoroncov, M; Karanam, B; Culhane, JC; Holbert, MA; Klein, DC; Abagyan, R; Cole, PA De novo discovery of serotonin N-acetyltransferase inhibitors. J Med Chem 50:5330-8 (2007) [PubMed]  Article 
Target
Name:
Serotonin N-acetyltransferase
Synonyms:
AANAT | SNAT | SNAT_SHEEP
Type:
PROTEIN
Mol. Mass.:
23086.34
Organism:
Ovis aries
Description:
ChEMBL_450671
Residue:
207
Sequence:
MSTPSVHCLKPSPLHLPSGIPGSPGRQRRHTLPANEFRCLTPEDAAGVFEIEREAFISVSGNCPLNLDEVQHFLTLCPELSLGWFVEGRLVAFIIGSLWDEERLTQESLALHRPRGHSAHLHALAVHRSFRQQGKGSVLLWRYLHHVGAQPAVRRAVLMCEDALVPFYQRFGFHPAGPCAIVVGSLTFTEMHCSLRGHAALRRNSDR
  
Inhibitor
Name:
BDBM50224328
Synonyms:
6-(4-oxo-5-(2-oxoindolin-3-yl)-2-thioxothiazolidin-3-yl)hexanoic acid | CHEMBL428025
Type:
Small organic molecule
Emp. Form.:
C17H18N2O4S2
Mol. Mass.:
378.466
SMILES:
OC(=O)CCCCCn1c(O)c(sc1=S)C1C(=O)Nc2ccccc12 |w:15.16|
Structure:
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