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Target
Macrophage infectivity potentiator
Ligand
BDBM50659606
Substrate
n/a
Meas. Tech.
ChEMBL_2627796
Kd
432±n/a nM
Citation
 Pérez Carrillo, VH; Whittaker, JJ; Wiedemann, C; Harder, JM; Lohr, T; Jamithireddy, AK; Dajka, M; Goretzki, B; Joseph, B; Guskov, A; Harmer, NJ; Holzgrabe, U; Hellmich, UA Structure and Dynamics of Macrophage Infectivity Potentiator Proteins from Pathogenic Bacteria and Protozoans Bound to Fluorinated Pipecolic Acid Inhibitors. J Med Chem 68:5926-5941[PubMed] 
Target
Name:
Macrophage infectivity potentiator
Synonyms:
5.2.1.8 | Macrophage infectivity potentiator | MIP | Peptidyl-prolyl cis-trans isomerase | PPIase | Rotamase
Type:
PROTEIN
Mol. Mass.:
22137.45
Organism:
Trypanosoma cruzi
Description:
ChEMBL_124041
Residue:
196
Sequence:
MHRENYFSKIAFCLLGVLFLSCITSVQTVSGDAASHEERMNNYRKRVGRLFMEQKAAQPDAVKLPSGLVFQRIARGSGKRAPAIDDKCEVHYTGRLRDGTVFDSSRERGKPTTFRPNEVIKGWTEALQLMREGDRWRLFIPYDLAYGVTGGGGMIPPYSPLEFDVELISIKDGGKGRTAEEVDEILRKAEEDREDM
  
Inhibitor
Name:
BDBM50659606
Synonyms:
CHEMBL5419108
Type:
Small organic molecule
Emp. Form.:
C25H33FN4O4S
Mol. Mass.:
504.63
SMILES:
CC(C)C[C@@H](C(=O)NCc1cccnc1)NC(=O)[C@@H]2CCCCN2S(=O)(=O)Cc3ccc(cc3)F
Structure:
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