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Target
DNA polymerase beta
Ligand
BDBM50259781
Substrate
n/a
Meas. Tech.
ChEMBL_524725 (CHEMBL980280)
IC50
3200±n/a nM
Citation
 Deng, JZ; Starck, SR; Hecht, SM DNA polymerase beta inhibitors from Baeckea gunniana. J Nat Prod 62:1624-6 (2000) [PubMed]  Article 
Target
Name:
DNA polymerase beta
Synonyms:
DNA Polymerase beta | DPOLB_RAT | Polb
Type:
PROTEIN
Mol. Mass.:
38334.34
Organism:
Rattus norvegicus
Description:
ChEMBL_1361926
Residue:
335
Sequence:
MSKRKAPQETLNGGITDMLVELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVTGIGPSAARKLVDEGIKTLEDLRKNEDKLNHHQRIGLKYFEDFEKRIPREEMLQMQDIVLNEVKKLDPEYIATVCGSFRRGAESSGDMDVLLTHPNFTSESSKQPKLLHRVVEQLQKVRFITDTLSKGETKFMGVCQLPSENDENEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEQDIFDYIQWRYREPKDRSE
  
Inhibitor
Name:
BDBM50259781
Synonyms:
3beta-hydroxyrus-12,19(29)-dien-28-oic acid | CHEMBL517522
Type:
Small organic molecule
Emp. Form.:
C30H46O3
Mol. Mass.:
454.6844
SMILES:
C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2C1=C)C(O)=O |r,c:9|
Structure:
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