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Target
Beta-mannosidase
Ligand
BDBM50242066
Substrate
n/a
Meas. Tech.
ChEMBL_550274 (CHEMBL1007622)
IC50
150000±n/a nM
Citation
 Asano, N; Ikeda, K; Kasahara, M; Arai, Y; Kizu, H Glycosidase-inhibiting pyrrolidines and pyrrolizidines with a long side chain in Scilla peruviana. J Nat Prod 67:846-50 (2004) [PubMed]  Article 
Target
Name:
Beta-mannosidase
Synonyms:
MANBA_RAT | Manba
Type:
PROTEIN
Mol. Mass.:
101229.60
Organism:
Rattus norvegicus
Description:
ChEMBL_41368
Residue:
881
Sequence:
MHLHLLFLLALCGAGCMAAGPSYSLRGSWRVSNGNSSLELPATVPGYVHSALQQHGLIQDPYYRFNDLNYRWISLDNWTYSTEFKIPFNRSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTRYSFDVTNVVKDVNSLKLRFQSAVQYAECQSKAHTQYRVPPECPPVEQKGECHVNFIRKEQCSFSWDWGPSFPSQGIWKDVRIEAYNIAHLDHLTFLPLYDNTSQAWTIEIEASFDVVSTKPVGGQVTIAIPELKTQQANHIELQHGQRIVKLLVKIRKDVTVETWWPHGHGNQTGYNTTILFALDGGLKIEKAAKVYFRTVQLIEEPITGSPGLSFYFKINGLPIFLKGSNWIPADSFQDKVTSELLQLLLQSAVDANMNTLRVWGGGIYEQDEFYALCDELGIMVWQDFMFASALYPTEPGFLESVRKEVTYQVRRLKSHPSVIIWSGNNENEVALRVNWFHVNPRDLGTYINDYVTLYVKTIREIVLSEDRSRPFIASSPTNGVKTMTEGWISKDPYSTQYGDMHFYDYFSDCWDWKVFPKARLVSEYGYQSWPSFSTLQKVSRQEDWSYSSRFSLHRQHHGNGNNEMLHQVQLHFQLPQRRDPVRAFKDTIYLTQVMQAQCIKTETEFYLRSRSEIVNGEGHTMGALYWQLNDIWQAPSWASLEYGGKWKMLHYFAQRFFAPLLPVGFEDEGVFYVYGVSDLHKDYPTKLTVRLHRWSSQKPLCTFVSLSAVIKAGEAMVLFQMPVSKLLKRCKECTRDTCVVSFYLSTDNELFSPTNYHFLSSLKDAKGMVKANITVSISQKGDLFVFDLKSSTSAITPFVWLDVGSIPGRFSDNGFLMIKKELSVLFYPWKPTSKSELQQAFSVTSLTDLY
  
Inhibitor
Name:
BDBM50242066
Synonyms:
CHEMBL511823 | alpha-1-C-(1,2-Dihdroxypropyl)-1,4-dideoxy-1,4-imino-D-arabinitol
Type:
Small organic molecule
Emp. Form.:
C8H17NO5
Mol. Mass.:
207.2243
SMILES:
CC(O)[C@@H](O)[C@H]1N[C@H](CO)[C@@H](O)[C@@H]1O |r|
Structure:
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