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Target
Beta-lactamase
Ligand
BDBM50021959
Substrate
n/a
Meas. Tech.
ChEMBL_516548 (CHEMBL985141)
IC50
9±n/a nM
Citation
 Queenan, AM; Shang, W; Kania, M; Page, MG; Bush, K Interactions of ceftobiprole with beta-lactamases from molecular classes A to D. Antimicrob Agents Chemother 51:3089-95 (2007) [PubMed]  Article 
Target
Name:
Beta-lactamase
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
31150.29
Organism:
Escherichia coli
Description:
ChEMBL_516548
Residue:
291
Sequence:
MVKKSLRQFTLMATATVTLLLGSVPLYAQTADVQQKLAELERQSGGRLGVALINTADNSQILYRADERFAMCSTSKVMAAAAVLKKSESEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGPASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRAQLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQPQPKAESRRDVLASAAKIVTDGL
  
Inhibitor
Name:
BDBM50021959
Synonyms:
CHEMBL777 | MM 14151 | US9120808, Clavulanic acid potassium salt | antibiotic MM 14151 | clavulanic acid
Type:
Small organic molecule
Emp. Form.:
C8H9NO5
Mol. Mass.:
199.1608
SMILES:
OC\C=C1/O[C@@H]2CC(=O)N2[C@H]1C(O)=O |r|
Structure:
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