Reaction Details Report a problem with these data
Target
Enoyl-[acyl-carrier-protein] reductase [NADH]
Ligand
BDBM16298
Substrate
n/a
Meas. Tech.
ChEMBL_532961 (CHEMBL989631)
Ki
1±n/a nM
Citation
 Gutierrez-Lugo, MT; Bewley, CA Natural products, small molecules, and genetics in tuberculosis drug development. J Med Chem 51:2606-12 (2008) [PubMed]  Article 
Target
Name:
Enoyl-[acyl-carrier-protein] reductase [NADH]
Synonyms:
Enoyl-ACP Reductase (InhA) | Enoyl-[acyl-carrier-protein] reductase | Enoyl-[acyl-carrier-protein] reductase [NADH] | INHA_MYCTU | NADH-dependent enoyl-ACP reductase | inhA
Type:
Enzyme
Mol. Mass.:
28526.00
Organism:
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Description:
P9WGR1
Residue:
269
Sequence:
MTGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL
  
Inhibitor
Name:
BDBM16298
Synonyms:
5-Octyl-2-phenoxy-phenol | 5-heptyl-2-phenoxylphenol | 5-octyl-2-phenoxyphenol | 8PP | AIDS227448 | CHEMBL505886 | PT05
Type:
Small organic molecule
Emp. Form.:
C20H26O2
Mol. Mass.:
298.4192
SMILES:
CCCCCCCCc1ccc(Oc2ccccc2)c(O)c1
Structure:
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