Reaction Details Report a problem with these data
Target
Adenosine kinase
Ligand
BDBM50252167
Substrate
n/a
Meas. Tech.
ChEMBL_491790 (CHEMBL937861)
Ki
82600±n/a nM
Citation
 Kim, YA; Sharon, A; Chu, CK; Rais, RH; Al Safarjalani, ON; Naguib, FN; el Kouni, MH Structure-activity relationships of 7-deaza-6-benzylthioinosine analogues as ligands of Toxoplasma gondii adenosine kinase. J Med Chem 51:3934-45 (2008) [PubMed]  Article 
Target
Name:
Adenosine kinase
Synonyms:
ADK_TOXGO | AK
Type:
PROTEIN
Mol. Mass.:
38353.04
Organism:
Toxoplasma gondii
Description:
ChEMBL_629062
Residue:
363
Sequence:
MAVDSSNSATGPMRVFAIGNPILDLVAEVPSSFLDEFFLKRGDATLATPEQMRIYSTLDQFNPTSLPGGSALNSVRVVQKLLRKPGSAGYMGAIGDDPRGQVLKELCDKEGLATRFMVAPGQSTGVCAVLINEKERTLCTHLGACGSFRLPEDWTTFASGALIFYATAYTLTATPKNALEVAGYAHGIPNAIFTLNLSAPFCVELYKDAMQSLLLHTNILFGNEEEFAHLAKVHNLVAAEKTALSTANKEHAVEVCTGALRLLTAGQNTGATKLVVMTRGHNPVIAAEQTADGTVVVHEVGVPVVAAEKIVDTNGAGDAFVGGFLYALSQGKTVKQCIMCGNACAQDVIQHVGFSLSFTSLPC
  
Inhibitor
Name:
BDBM50252167
Synonyms:
4-Benzylthio-5-iodo-7-(beta-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidin | CHEMBL481317
Type:
Small organic molecule
Emp. Form.:
C18H18IN3O4S
Mol. Mass.:
499.323
SMILES:
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cc(I)c2c(SCc3ccccc3)ncnc12 |r|
Structure:
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