Reaction Details Report a problem with these data
Target
Group IIF secretory phospholipase A2
Ligand
BDBM50055391
Substrate
n/a
Meas. Tech.
ChEMBL_489277 (CHEMBL990833)
IC50
470±n/a nM
Citation
 Oslund, RC; Cermak, N; Gelb, MH Highly specific and broadly potent inhibitors of mammalian secreted phospholipases A2. J Med Chem 51:4708-14 (2008) [PubMed]  Article 
Target
Name:
Group IIF secretory phospholipase A2
Synonyms:
PA2GF_MOUSE | Pla2g2f
Type:
PROTEIN
Mol. Mass.:
18878.78
Organism:
Mus musculus
Description:
ChEMBL_489277
Residue:
168
Sequence:
MKKFFAIAVLAGSVVTTAHSSLLNLKSMVEAITHRNSILSFVGYGCYCGLGGRGHPMDEVDWCCHAHDCCYEKLFEQGCRPYVDHYDHRIENGTMIVCTELNETECDKQTCECDKSLTLCLKDHPYRNKYRGYFNVYCQGPTPNCSIYDPYPEEVTCGHGLPATPVST
  
Inhibitor
Name:
BDBM50055391
Synonyms:
2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yloxy)propanoic acid | 2-(3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-propionic acid | CHEMBL148649
Type:
Small organic molecule
Emp. Form.:
C22H22N2O5
Mol. Mass.:
394.4205
SMILES:
CCc1c(C(=O)C(N)=O)c2c(OC(C)C(O)=O)cccc2n1Cc1ccccc1
Structure:
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