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Target
Galanin receptor type 1
Ligand
BDBM50256664
Substrate
n/a
Meas. Tech.
ChEMBL_515047 (CHEMBL1034789)
IC50
20.4±n/a nM
Citation
 Terui, Y; Chu, YW; Li, JY; Ando, T; Fukunaga, T; Aoki, T; Toda, Y New cyclic tetrapeptides from Nonomuraea sp. TA-0426 that inhibit glycine transporter type 1 (GlyT1). Bioorg Med Chem Lett 18:6321-3 (2008) [PubMed]  Article 
Target
Name:
Galanin receptor type 1
Synonyms:
GALR1_RAT | Galanin R1 | Galanin receptor type 1 | Galnr | Galnr1 | Galr1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38883.91
Organism:
RAT
Description:
Galanin R1 GALR1 RAT::Q62805
Residue:
346
Sequence:
MELAPVNLSEGNGSDPEPPAEPRPLFGIGVENFITLVVFGLIFAMGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGFIWALSIAMASPVAYYQRLFHRDSNQTFCWEHWPNQLHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHLHKKLKNMSKKSEASKKKTAQTVLVVVVVFGISWLPHHVIHLWAEFGAFPLTPASFFFRITAHCLAYSNSSVNPIIYAFLSENFRKAYKQVFKCRVCNESPHGDAKEKNRIDTPPSTNCTHV
  
Inhibitor
Name:
BDBM50256664
Synonyms:
(S)-2-((2S,5S,8S,11S)-5-benzyl-8,11-di-sec-butyl-3,6,9,12-tetraoxo-1,4,7,10-tetraazacyclododecan-2-yl)-3-oxobutane-1-sulfonic acid | CHEMBL475845
Type:
Small organic molecule
Emp. Form.:
C27H40N4O8S
Mol. Mass.:
580.693
SMILES:
CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)[C@@H](C)CC)[C@H](CS(O)(=O)=O)C(C)=O |r|
Structure:
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