Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50255055
Substrate
n/a
Meas. Tech.
ChEMBL_558496 (CHEMBL963902)
IC50
>10000±n/a nM
Citation
 Kim, JY; Seo, HJ; Lee, SH; Jung, ME; Ahn, K; Kim, J; Lee, J Diarylimidazolyl oxadiazole and thiadiazole derivatives as cannabinoid CB1 receptor antagonists. Bioorg Med Chem Lett 19:142-5 (2008) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50255055
Synonyms:
2-(1-(4-bromophenyl)-2-(2,4-dichlorophenyl)-5-ethyl-1H-imidazol-4-yl)-5-(1-(2,4-dichlorophenyl)cyclopropyl)-1,3,4-thiadiazole | CHEMBL480405
Type:
Small organic molecule
Emp. Form.:
C28H19BrCl4N4S
Mol. Mass.:
665.258
SMILES:
CCc1c(nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Br)cc1)-c1nnc(s1)C1(CC1)c1ccc(Cl)cc1Cl
Structure:
Search PDB for entries with ligand similarity: