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Target
Ribokinase
Ligand
BDBM50255451
Substrate
n/a
Meas. Tech.
ChEMBL_515843 (CHEMBL1030542)
IC50
>300000±n/a nM
Citation
 Desroy, N; Moreau, F; Briet, S; Le Fralliec, G; Floquet, S; Durant, L; Vongsouthi, V; Gerusz, V; Denis, A; Escaich, S Towards Gram-negative antivirulence drugs: new inhibitors of HldE kinase. Bioorg Med Chem 17:1276-89 (2009) [PubMed]  Article 
Target
Name:
Ribokinase
Synonyms:
RBSK_ECOLI | rbsK
Type:
PROTEIN
Mol. Mass.:
32281.04
Organism:
Escherichia coli (strain K12)
Description:
ChEMBL_515843
Residue:
309
Sequence:
MQNAGSLVVLGSINADHILNLQSFPTPGETVTGNHYQVAFGGKGANQAVAAGRSGANIAFIACTGDDSIGESVRQQLATDNIDITPVSVIKGESTGVALIFVNGEGENVIGIHAGANAALSPALVEAQRERIANASALLMQLESPLESVMAAAKIAHQNKTIVALNPAPARELPDELLALVDIITPNETEAEKLTGIRVENDEDAAKAAQVLHEKGIRTVLITLGSRGVWASVNGEGQRVPGFRVQAVDTIAAGDTFNGALITALLEEKPLPEAIRFAHAAAAIAVTRKGAQPSVPWREEIDAFLDRQR
  
Inhibitor
Name:
BDBM50255451
Synonyms:
CHEMBL480811 | [{[2-(3-Methoxyphenyl)-5-methyl-1,3-oxazol-4-yl]carbonyl}(pyridin-2-ylmethyl)amino]acetic acid
Type:
Small organic molecule
Emp. Form.:
C20H19N3O5
Mol. Mass.:
381.382
SMILES:
COc1cccc(c1)-c1nc(C(=O)N(CC(O)=O)Cc2ccccn2)c(C)o1
Structure:
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