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Target
Prostaglandin D2 receptor
Ligand
BDBM50277479
Substrate
n/a
Meas. Tech.
ChEMBL_501282 (CHEMBL971468)
Ki
1±n/a nM
Citation
 Leblanc, Y; Roy, P; Dufresne, C; Lachance, N; Wang, Z; O'Neill, G; Greig, G; Denis, D; Mathieu, MC; Slipetz, D; Sawyer, N; Tsou, N Discovery of potent and selective DP1 receptor antagonists in the azaindole series. Bioorg Med Chem Lett 19:2125-8 (2009) [PubMed]  Article 
Target
Name:
Prostaglandin D2 receptor
Synonyms:
PD2R_HUMAN | PTGDR | Prostaglandin D2 | Prostaglandin D2 receptor | Prostanoid DP receptor
Type:
Enzyme
Mol. Mass.:
40288.87
Organism:
Homo sapiens (Human)
Description:
Q13258
Residue:
359
Sequence:
MKSPFYRCQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPSVFYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLSSTLQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQYCPGTWCFIQMVHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRHPRSCTRDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAFKDVKEKNRTSEEAEDLRALRFLSVISIVDPWIFIIFRSPVFRIFFHKIFIRPLRYRSRCSNSTNMESSL
  
Inhibitor
Name:
BDBM50277479
Synonyms:
2-(9-(3,4-dichlorophenylthio)-1-phenyl-7,8-dihydro-6H-pyrido[3,4-b]pyrrolizin-8-yl)acetic acid | CHEMBL514964
Type:
Small organic molecule
Emp. Form.:
C24H18Cl2N2O2S
Mol. Mass.:
469.383
SMILES:
OC(=O)CC1CCn2c1c(Sc1ccc(Cl)c(Cl)c1)c1c(nccc21)-c1ccccc1
Structure:
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