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Target
Vasopressin V2 receptor
Ligand
BDBM50281512
Substrate
n/a
Meas. Tech.
ChEBML_215042
IC50
>100000±n/a nM
Citation
 Salituro, GM; Pettibone, DJ; Clineschmidt, BV; Williamson, JM; Zink, DL Potent, non-peptidic oxytocin receptor antagonists from a natural source Bioorg Med Chem Lett 3:337-340 (1993)    Article 
Target
Name:
Vasopressin V2 receptor
Synonyms:
AVPR2 | V2R_PIG
Type:
PROTEIN
Mol. Mass.:
40556.17
Organism:
Sus scrofa
Description:
ChEMBL_214870
Residue:
370
Sequence:
MLRATTSAVPRALSWPAAPGNGSEREPLDDRDPLLARVELALLSTVFVAVALSNGLVLGALVRRGRRGRWAPMHVFIGHLCLADLAVALFQVLPQLAWDATYRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGGGARWNRPVLVAWAFSLLLSLPQLFIFAQRDVGDGSGVLDCWASFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHTSLVPGPAERAGGHRGGRRAGSPREGARVSAAMAKTARMTLVIVAVYVLCWAPFFLVQLWSVWDPKAPREGPPFVLLMLLASLNSCTNPWIYASFSSSISSELRSLLCCPRRRTPPSLRPQEESCATASSFSARDTSS
  
Inhibitor
Name:
BDBM50281512
Synonyms:
Acetic acid (S)-1-(4,11-dimethoxy-9-methyl-5-oxo-5H,7H-6,12-dioxa-dibenzo[a,d]cycloocten-3-yl)-3-methyl-butyl ester | CHEMBL326085
Type:
Small organic molecule
Emp. Form.:
C24H28O7
Mol. Mass.:
428.4749
SMILES:
COc1cc(C)cc2COC(=O)c3c(Oc12)ccc([C@H](CC(C)C)OC(C)=O)c3OC
Structure:
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