Reaction Details Report a problem with these data
Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50282111
Substrate
n/a
Meas. Tech.
ChEMBL_157860 (CHEMBL764749)
Ki
5000±n/a nM
Citation
 Beresis, R; Panek, JS A concise enantioselective synthesis of rans-olefin dipeptide isosteres Bioorg Med Chem Lett 3:1609-1614 (1993)    Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50282111
Synonyms:
(S)-2-[(E)-(2R,5S)-2-Benzyl-5-((S)-1-methoxycarbonyl-2-methyl-propylcarbamoyl)-6-methyl-hept-3-enoylamino]-3-methyl-butyric acid | CHEMBL290265
Type:
Small organic molecule
Emp. Form.:
C28H42N2O6
Mol. Mass.:
502.6429
SMILES:
COC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)\C=C\[C@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)OC)C(C)C
Structure:
Search PDB for entries with ligand similarity: