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Target
Type-1 angiotensin II receptor B
Ligand
BDBM50282271
Substrate
n/a
Meas. Tech.
ChEMBL_34830 (CHEMBL648764)
IC50
230±n/a nM
Citation
 Perreaut, P; Clément, J; Muneaux, C; Muneaux, Y; Cazaubon, C; Gougat, J; Guiraudou, P; Lacour, C; Nisato, D; Fur, GL; Breliere, JC Dihydro-imidazolone derivatives as angiotensin II receptor antagonists: chiral effect on the activity Bioorg Med Chem Lett 4:163-168 (1994)    Article 
Target
Name:
Type-1 angiotensin II receptor B
Synonyms:
AGTRB_RAT | AT3 | Agtr1 | Agtr1b | Angiotensin II AT1B | Angiotensin II receptor (AT-1) type-1 | Angiotensin II type 1b (AT-1b) receptor | At1b | Type-1B angiotensin II receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40929.44
Organism:
RAT
Description:
Angiotensin II AT1B 0 RAT::P29089
Residue:
359
Sequence:
MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE
  
Inhibitor
Name:
BDBM50282271
Synonyms:
4'-[2-Butyl-4-(2,4-dimethyl-pentyl)-4-methyl-5-oxo-4,5-dihydro-imidazol-1-ylmethyl]-biphenyl-2-carboxylic acid | CHEMBL48392
Type:
Small organic molecule
Emp. Form.:
C29H38N2O3
Mol. Mass.:
462.6236
SMILES:
CCCCC1=NC(C)(CC(C)CC(C)C)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:4|
Structure:
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