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Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50283114
Substrate
n/a
Meas. Tech.
ChEMBL_201427 (CHEMBL810660)
Ki
19±n/a nM
Citation
 Hudkins, RL; DeHaven-Hudkins, DL Phenytoin derivatives as potent σ ligands Bioorg Med Chem Lett 4:2185-2188 (1994)    Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25124.85
Organism:
Homo sapiens (Human)
Description:
Q99720
Residue:
223
Sequence:
MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50283114
Synonyms:
5,5-Diphenyl-3-[5-(4-phenyl-piperazin-1-yl)-pentyl]-imidazolidine-2,4-dione | CHEMBL302096
Type:
Small organic molecule
Emp. Form.:
C30H34N4O2
Mol. Mass.:
482.6166
SMILES:
O=C1NC(C(=O)N1CCCCCN1CCN(CC1)c1ccccc1)(c1ccccc1)c1ccccc1
Structure:
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