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Target
Type-2 angiotensin II receptor
Ligand
BDBM50283248
Substrate
n/a
Meas. Tech.
ChEBML_35562
IC50
1.6±n/a nM
Citation
 Santella, JB; Duncia, JV; Ensinger, CL; VanAtten, MK; Carini, DJ; Wexler, RR; Chiu, AT; Wong, PC; Timmermans, PB Balanced angiotensin II receptor antagonists. III. The effects of substitution at the imidazole 5-position. Bioorg Med Chem Lett 4:2235-2240 (1994)    Article 
Target
Name:
Type-2 angiotensin II receptor
Synonyms:
AGTR2 | AGTR2_HUMAN | AT2 | Angiotensin II receptor | Angiotensin II type 2 (AT-2) receptor | Angiotensin II, central | Type-2 angiotensin II receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41201.61
Organism:
Homo sapiens (Human)
Description:
Angiotensin II, central 0 0::P50052
Residue:
363
Sequence:
MKGNSTLATTSKNITSGLHFGLVNISGNNESTLNCSQKPSDKHLDAIPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRESMSCRKSSSLREMETFVS
  
Inhibitor
Name:
BDBM50283248
Synonyms:
Biphenylsulfonylcarbamate compound | CHEMBL70726
Type:
Small organic molecule
Emp. Form.:
C40H40FN3O7S
Mol. Mass.:
725.825
SMILES:
CCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCC)nc(CC)c2C(=O)OCc2ccccc2C(=O)c2ccccc2)c(F)c1
Structure:
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