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Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50283819
Substrate
n/a
Meas. Tech.
ChEBML_79969
Ki
340±n/a nM
Citation
 Ettmayer, P; Hübner, M; Andreas, B; Brigitte, R; Hubert, G Novel, extended transition state mimic in HIV-1 protease inhibitors with peripheral C-2-symmetry Bioorg Med Chem Lett 4:2851-2856 (1994)    Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50283819
Synonyms:
CHEMBL96038 | {(S)-1-[(1S,2S,3S,4S)-1-Benzyl-4-((S)-2-benzyloxycarbonylamino-3-carbamoyl-propionylamino)-2-hydroxy-3-hydroxymethyl-5-phenyl-pentylcarbamoyl]-2-methyl-propyl}-carbamic acid benzyl ester
Type:
Small organic molecule
Emp. Form.:
C44H53N5O9
Mol. Mass.:
795.9197
SMILES:
CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)[C@H](CO)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)OCc1ccccc1
Structure:
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