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Target
Neuromedin-K receptor
Ligand
BDBM50283960
Substrate
n/a
Meas. Tech.
ChEMBL_209390 (CHEMBL811322)
IC50
10000±n/a nM
Citation
 Horwell, DC; Lennon, IC; Roberts, E Alternative strategies towards the identification of chemical lead compounds by rational design Bioorg Med Chem Lett 4:525-530 (1994)    Article 
Target
Name:
Neuromedin-K receptor
Synonyms:
NK3R_CAVPO | Neurokinin 3 receptor | Neurokinin NK3 | Neuromedin-K receptor | TACR3
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49456.44
Organism:
GUINEA PIG
Description:
Neurokinin NK3 TACR3 GUINEA PIG::P30098
Residue:
440
Sequence:
MASPAGNLSAWPGWGWPPPAALRNLTSSPAPTASPSPAPSWTPSPRPGPAHPFLQPPWAVALWSLAYGAVVAVAVLGNLVVIWIVLAHKRMRTVTNSFLVNLAFADAAMAALNALVNFIYALHGEWYFGANYCRFQNFFPITAVFASIYSMTAIAVDRYMAIIDPLKPRLSATATRIVIGSIWILAFLLAFPQCLYSKIKVMPGRTLCYVQWPEGSRQHFTYHMIVIVLVYCFPLLIMGITYTIVGITLWGGEIPGDTCDKYQEQLKAKRKVVKMMIIVVVTFAICWLPYHIYFILTAIYQQLNRWKYIQQVYLASFWLAMSSTMYNPIIYCCLNKRFRAGFKRAFRWCPFIHVSSYDELELKATRLHPMRQSSLYTVTRMESMSVVFDSNDGDSARSSHQKRGTTRDVGSNVCSRRNSKSTSTTASFVSSSHMSVEEGS
  
Inhibitor
Name:
BDBM50283960
Synonyms:
1-Benzyl-3-(1H-indol-3-ylmethyl)-piperidin-4-one | CHEMBL151990
Type:
Small organic molecule
Emp. Form.:
C21H22N2O
Mol. Mass.:
318.4122
SMILES:
O=C1CCN(Cc2ccccc2)CC1Cc1c[nH]c2ccccc12
Structure:
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