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Target
Platelet-activating factor receptor
Ligand
BDBM50284405
Substrate
n/a
Meas. Tech.
ChEMBL_162887 (CHEMBL768983)
IC50
1140±n/a nM
Citation
 Chung, SK; Ban, SH; Kim, SH; Kim, BE; Woo, SH; Summers, JB; Conway, RG Synthesis and bioactivities of heterocyclic lipids as PAF antagonists. 1 Bioorg Med Chem Lett 5:1091-1096 (1995)    Article 
Target
Name:
Platelet-activating factor receptor
Synonyms:
PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor
Type:
Protein
Mol. Mass.:
39005.63
Organism:
Cavia porcellus
Description:
n/a
Residue:
342
Sequence:
MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLTVADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVKYPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKGSKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAVFVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
  
Inhibitor
Name:
BDBM50284405
Synonyms:
3-[4-(1-Octadecylcarbamoyloxymethyl-cyclopentylmethoxycarbonyl)-butyl]-thiazol-3-ium; bromide | CHEMBL275573
Type:
Small organic molecule
Emp. Form.:
C34H61N2O4S
Mol. Mass.:
593.924
SMILES:
CCCCCCCCCCCCCCCCCCNC(=O)OCC1(COC(=O)CCCC[n+]2ccsc2)CCCC1
Structure:
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