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Target
Delta-type opioid receptor
Ligand
BDBM50284885
Substrate
n/a
Meas. Tech.
ChEMBL_146639 (CHEMBL754320)
EC50
402±n/a nM
Citation
 Sagara, T; Okamura, M; Shimohigashi, Y; Ohno, M; Kanematsu, K Specific affinity labeling of μ opioid receptors in rat brain by S-activated sulfhydryldihydromorphine analogs Bioorg Med Chem Lett 5:1609-1614 (1995)    Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
Cytochrome P450 3A4 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor | Delta-type opioid receptor (DOR) | OPIATE Delta | OPRD_RAT | Opiate Delta 1 | Opioid receptor | Opioid receptor A | Opioid receptors; mu & delta | Oprd1 | Ror-a | Voltage-gated potassium channel
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40465.04
Organism:
Rattus norvegicus (rat)
Description:
Competition binding assays were using CHO-K1 cell membranes expressing the opioid receptor.
Residue:
372
Sequence:
MEPVPSARAELQFSLLANVSDTFPSAFPSASANASGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTQPRDGAVVCTLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRAPCGGQEPGSLRRPRQATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50284885
Synonyms:
4-methyl-14-(5-nitro-2-pyridyldisulfanyl)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-10-ol | CHEMBL40643
Type:
Small organic molecule
Emp. Form.:
C22H23N3O4S2
Mol. Mass.:
457.566
SMILES:
CN1CC[C@@]23[C@H]4Oc5c2c(CC1C3CC[C@H]4SSc1ccc(cn1)[N+]([O-])=O)ccc5O |TLB:7:8:12:1.3.2,27:9:12:1.3.2|
Structure:
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