Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 1D
Ligand
BDBM50285523
Substrate
n/a
Meas. Tech.
ChEBML_1651
EC50
14±n/a nM
Citation
 Macor, JE; Blank, DH; Desai, K; Fox, CB; Koe, BK; Lebel, LA; Post, RJ; Schmidt, AW; Schulz, DW; Seymour, PA 5-cyano-1-[3-(N-methylpyrrolidin-2R-ylmethyl)indol-5-yl] benzimidazole (CP-161,242): A potent, centrally active 5-HT1D receptor agonist and benzodiazepine partial agonist Bioorg Med Chem Lett 5:2391-2396 (1995)    Article 
Target
Name:
5-hydroxytryptamine receptor 1D
Synonyms:
5-HT1D | 5-hydroxytryptamine receptor 1D | 5HT1D_CAVPO | HTR1D | Serotonin 1d (5-HT1d) receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41780.38
Organism:
GUINEA PIG
Description:
5-HT1D HTR1D GUINEA PIG::Q60484
Residue:
376
Sequence:
MSPPNQSEEGLPQEASNRSLNATETPGDWDPGLLQALKVSLVVVLSIITLATVLSNAFVLTTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTTTRTWNFGQILCDIWVSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAGAMIAAVWVISICISIPPLFWRQAQAQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYSRIYRAARSRILNPPSLSGKRFTTAHLITGSAGSSLCSLNPSLHEGHMHPGSPLFFNHVRIKLADSVLERKRISAARERKATKTLGIILGAFIVCWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEDFRQAFQKVVHFRKAS
  
Inhibitor
Name:
BDBM50285523
Synonyms:
CHEMBL80189 | [2-(5-Imidazo[4,5-b]pyridin-3-yl-1H-indol-3-yl)-ethyl]-dimethyl-amine
Type:
Small organic molecule
Emp. Form.:
C18H19N5
Mol. Mass.:
305.377
SMILES:
CN(C)CCc1c[nH]c2ccc(cc12)-n1cnc2cccnc12
Structure:
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