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Target
Chymotrypsinogen B
Ligand
BDBM50287590
Substrate
n/a
Meas. Tech.
ChEMBL_216624 (CHEMBL819196)
pH
7.8±n/a
Ki
460000±n/a nM
Comments
extracted
Citation
 Ohba, T; Ikeda, E; Takei, H Inactivation of serine protease, α-chymotrypsin by fluorinated phenylalanine analogues Bioorg Med Chem Lett 6:1875-1880 (1996)    Article 
Target
Name:
Chymotrypsinogen B
Synonyms:
Beta-chymotrypsin | CTRB | CTRB1 | CTRB1_HUMAN | Chymotrypsin B chain A | Chymotrypsin B chain B | Chymotrypsin B chain C | Chymotrypsinogen B | Synonyms=CTRB
Type:
PROTEIN
Mol. Mass.:
27713.98
Organism:
Homo sapiens (Human)
Description:
ChEMBL_10909
Residue:
263
Sequence:
MASLWLLSCFSLVGAAFGCGVPAIHPVLSGLSRIVNGEDAVPGSWPWQVSLQDKTGFHFCGGSLISEDWVVTAAHCGVRTSDVVVAGEFDQGSDEENIQVLKIAKVFKNPKFSILTVNNDITLLKLATPARFSQTVSAVCLPSADDDFPAGTLCATTGWGKTKYNANKTPDKLQQAALPLLSNAECKKSWGRRITDVMICAGASGVSSCMGDSGGPLVCQKDGAWTLVGIVSWGSDTCSTSSPGVYARVTKLIPWVQKILAAN
  
Inhibitor
Name:
BDBM50287590
Synonyms:
CHEMBL291936 | N-((S)-1-Benzyl-2,2-difluoro-but-3-enyl)-acetamide
Type:
Small organic molecule
Emp. Form.:
C13H15F2NO
Mol. Mass.:
239.2611
SMILES:
CC(=O)N[C@@H](Cc1ccccc1)C(F)(F)C=C
Structure:
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