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Target
Tissue alpha-L-fucosidase
Ligand
BDBM50104398
Substrate
n/a
Meas. Tech.
ChEBML_33958
Ki
3300±n/a nM
Citation
 Tsuruta, O; Yuasa, H; Hashimoto, H p-Nitrophenyl 1,5-dithio-alpha-L-fucopyranoside: a novel sulfur based fucosidase inhibitor Bioorg Med Chem Lett 6:1989-1992 (1996)    Article 
Target
Name:
Tissue alpha-L-fucosidase
Synonyms:
Alpha-L-fucosidase I | Alpha-L-fucoside fucohydrolase | FUCA1 | FUCO_HUMAN | Tissue alpha-L-fucosidase
Type:
PROTEIN
Mol. Mass.:
53690.69
Organism:
Homo sapiens (Human)
Description:
ChEMBL_34088
Residue:
466
Sequence:
MRAPGMRSRPAGPALLLLLLFLGAAESVRRAQPPRRYTPDWPSLDSRPLPAWFDEAKFGVFIHWGVFSVPAWGSEWFWWHWQGEGRPQYQRFMRDNYPPGFSYADFGPQFTARFFHPEEWADLFQAAGAKYVVLTTKHHEGFTNWPSPVSWNWNSKDVGPHRDLVGELGTALRKRNIRYGLYHSLLEWFHPLYLLDKKNGFKTQHFVSAKTMPELYDLVNSYKPDLIWSDGEWECPDTYWNSTNFLSWLYNDSPVKDEVVVNDRWGQNCSCHHGGYYNCEDKFKPQSLPDHKWEMCTSIDKFSWGYRRDMALSDVTEESEIISELVQTVSLGGNYLLNIGPTKDGLIVPIFQERLLAVGKWLSINGEAIYASKPWRVQWEKNTTSVWYTSKGSAVYAIFLHWPENGVLNLESPITTSTTKITMLGIQGDLKWSTDPDKGLFISLPQLPPSAVPAEFAWTIKLTGVK
  
Inhibitor
Name:
BDBM50104398
Synonyms:
(R)-2-Methyl-6-(4-nitro-phenylsulfanyl)-tetrahydro-thiopyran-3,4,5-triol | CHEMBL314581
Type:
Small organic molecule
Emp. Form.:
C12H15NO5S2
Mol. Mass.:
317.381
SMILES:
CC1SC(Sc2ccc(cc2)[N+]([O-])=O)C(O)[C@H](O)C1O
Structure:
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