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Target
Protein kinase C eta type
Ligand
BDBM50280454
Substrate
n/a
Meas. Tech.
ChEBML_161130
Ki
3.4±n/a nM
Citation
 Irie, K; Yanai, Y; Ohigashi, H; Wender, PA; Miller, BL Synthesis and characterization of the second cysteine-rich region of mouse skin PKCGh Bioorg Med Chem Lett 6:353-356 (1996)    Article 
Target
Name:
Protein kinase C eta type
Synonyms:
KPCL_MOUSE | Pkch | Prkch | Protein kinase C eta
Type:
PROTEIN
Mol. Mass.:
77933.38
Organism:
Mus musculus
Description:
ChEMBL_161130
Residue:
683
Sequence:
MSSGTMKFNGYLRVRIGEAVGLQPTRWSLRHSLFKKGHQLLDPYLTVSVDQVRVGQTSTKQKTNKPTYNEEFCANVTDGGHLELAVFHETPLGYDHFVANCTLQFQELLRTAGTSDTFEGWVDLEPEGKVFVVITLTGSFTEATLQRDRIFKHFTRKRQRAMRRRVHQVNGHKFMATYLRQPTYCSHCREFIWGVFGKQGYQCQVCTCVVHKRCHHLIVTACTCQNNINKVDAKIAEQRFGINIPHKFNVHNYKVPTFCDHCGSLLWGIMRQGLQCKICKMNVHIRCQANVAPNCGVNAVELAKTLAGMGLQPGNISPTSKLISRSTLRRQGKEGSKEGNGIGVNSSSRFGIDNFEFIRVLGKGSFGKVMLARIKETGELYAVKVLKKDVILQDDDVECTMTEKRILSLARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHEKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTATFCGTPDYIAPEILQEMLYGPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGILKSFMTKNPTMRLGSLTQGGEHEILRHPFFKEIDWAQLNHRQLEPPFRPRIKSREDVSNFDPDFIKEEPVLTPIDEGHLPMINQDEFRNFSYVSPELQL
  
Inhibitor
Name:
BDBM50280454
Synonyms:
(10S,13S)-13-Hydroxymethyl-10-isopropyl-9-methyl-3,9,12-triaza-tricyclo[6.6.1.0*4,15*]pentadeca-4,6,8(15)-trien-11-one | CHEMBL120645
Type:
Small organic molecule
Emp. Form.:
C17H25N3O2
Mol. Mass.:
303.3993
SMILES:
CC(C)[C@@H]1N(C)c2cccc3NCC(C[C@@H](CO)NC1=O)c23
Structure:
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