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Target
Beta-lactamase
Ligand
BDBM50290040
Substrate
n/a
Meas. Tech.
ChEBML_40408
IC50
4±n/a nM
Citation
 Pfaendler, HR; Weishaupt, R; Medicus, C Synthesis and biological activity of novel penem sulfoxides and sulfones Bioorg Med Chem Lett 7:2217-2222 (1997)    Article 
Target
Name:
Beta-lactamase
Synonyms:
AMPC_ENTCL | ampC
Type:
PROTEIN
Mol. Mass.:
41306.67
Organism:
Enterobacter cloacae
Description:
ChEMBL_40258
Residue:
381
Sequence:
MMRKSLCCALLLGISCSALATPVSEKQLAEVVANTITPLMKAQSVPGMAVAVIYQGKPHYYTFGKADIAANKPVTPQTLFELGSISKTFTGVLGGDAIARGEISLDDAVTRYWPQLTGKQWQGIRMLDLATYTAGGLPLQVPDEVTDNASLLRFYQNWQPQWKPGTTRLYANASIGLFGALAVKPSGMPYEQAMTTRVLKPLKLDHTWINVPKAEEAHYAWGYRDGKAVRVSPGMLDAQAYGVKTNVQDMANWVMANMAPENVADASLKQGIALAQSRYWRIGSMYQGLGWEMLNWPVEANTVVEGSDSKVALAPLPVAEVNPPAPPVKASWVHKTGSTGGFGSYVAFIPEKQIGIVMLANTSYPNPARVEAAYHILEALQ
  
Inhibitor
Name:
BDBM50290040
Synonyms:
CHEMBL67925 | Potassium; (5R,6S)-3-tert-butyl-6-((R)-1-hydroxy-ethyl)-4,4,7-trioxo-4lambda*6*-thia-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylate
Type:
Small organic molecule
Emp. Form.:
C12H16NO6S
Mol. Mass.:
302.324
SMILES:
C[C@@H](O)[C@@H]1[C@@H]2N(C1=O)C(C([O-])=O)=C(C(C)(C)C)S2(=O)=O |t:12|
Structure:
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