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Target
Ras-related C3 botulinum toxin substrate 1
Ligand
BDBM50293841
Substrate
n/a
Meas. Tech.
ChEMBL_572380 (CHEMBL1035281)
IC50
12200±n/a nM
Citation
 Ferri, N; Corsini, A; Bottino, P; Clerici, F; Contini, A Virtual screening approach for the identification of new Rac1 inhibitors. J Med Chem 52:4087-90 (2009) [PubMed]  Article 
Target
Name:
Ras-related C3 botulinum toxin substrate 1
Synonyms:
RAC1 | RAC1_HUMAN | Ras-related C3 botulinum toxin substrate 1 | Ras-related C3 botulinum toxin substrate 1/T-lymphoma invasion and metastasis-inducing protein 1 | TC25
Type:
PROTEIN
Mol. Mass.:
21455.91
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1337921
Residue:
192
Sequence:
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
  
Inhibitor
Name:
BDBM50293841
Synonyms:
3-((3,5-dimethylisoxazol-4-yl)methoxy)-N-(4-methyl-3-(methylsulfonyl)phenyl)benzamide | CHEMBL558673
Type:
Small organic molecule
Emp. Form.:
C21H22N2O5S
Mol. Mass.:
414.475
SMILES:
Cc1noc(C)c1COc1cccc(c1)C(=O)Nc1ccc(C)c(c1)S(C)(=O)=O
Structure:
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