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Target
Baculoviral IAP repeat-containing protein 5
Ligand
BDBM26673
Substrate
n/a
Meas. Tech.
ChEMBL_588651 (CHEMBL1056061)
Kd
5700±n/a nM
Citation
 Abadi, AH; Abouel-Ella, DA; Lehmann, J; Tinsley, HN; Gary, BD; Piazza, GA; Abdel-Fattah, MA Discovery of colon tumor cell growth inhibitory agents through a combinatorial approach. Eur J Med Chem 45:90-7 (2010) [PubMed]  Article 
Target
Name:
Baculoviral IAP repeat-containing protein 5
Synonyms:
API4 | Apoptosis inhibitor 4 | Apoptosis inhibitor survivin | BIRC5 | BIRC5_HUMAN | IAP4
Type:
PROTEIN
Mol. Mass.:
16386.52
Organism:
Homo sapiens (Human)
Description:
ChEMBL_443470
Residue:
142
Sequence:
MGAPTLPPAWQPFLKDHRISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDDDPIEEHKKHSSGCAFLSVKKQFEELTLGEFLKLDRERAKNKIAKETNNKKKEFEETAKKVRRAIEQLAAMD
  
Inhibitor
Name:
BDBM26673
Synonyms:
6-(5-bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile | CHEMBL391586 | pyridone-based compound, 1
Type:
Small organic molecule
Emp. Form.:
C18H11BrN2O2
Mol. Mass.:
367.196
SMILES:
Oc1ccc(Br)cc1-c1cc(-c2ccccc2)c(C#N)c(=O)[nH]1
Structure:
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