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Target
Amine oxidase [flavin-containing] A
Ligand
BDBM15613
Substrate
n/a
Meas. Tech.
ChEMBL_601025 (CHEMBL1069162)
Ki
5.53±n/a nM
Citation
 Gökhan-Kelekçi, N; Simsek, OO; Ercan, A; Yelekçi, K; Sahin, ZS; Isik, S; Uçar, G; Bilgin, AA Synthesis and molecular modeling of some novel hexahydroindazole derivatives as potent monoamine oxidase inhibitors. Bioorg Med Chem 17:6761-72 (2009) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] A
Synonyms:
AOFA_RAT | Amine oxidase (flavin-containing) A | Amine oxidase [flavin-containing] A | Maoa | Monoamine Oxidase Type A (MAO-A) | Monoamine oxidase | Monoamine oxidase A (MAO-A) | Monoamine oxidase A (rMAO-A) | Monoamine oxidase type A (MAOA)
Type:
Enzyme
Mol. Mass.:
59515.21
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
526
Sequence:
MTDLEKPNLAGHMFDVGLIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVKWVDVGGAYVGPTQNRILRLSKELGIETYKVNVNERLVQYVKGKTYPFRGAFPPVWNPLAYLDYNNLWRTMDEMGKEIPVDAPWQARHAQEWDKMTMKDLIDKICWTKTAREFAYLFVNINVTSEPHEVSALWFLWYVRQCGGTARIFSVTNGGQERKFVGGSGQVSEQIMGLLGDKVKLSSPVTYIDQTDDNIIVETLNHEHYECKYVISAIPPILTAKIHFKPELPPERNQLIQRLPMGAVIKCMVYYKEAFWKKKDYCGCMIIEDEEAPIAITLDDTKPDGSLPAIMGFILARKADRQAKLHKDIRKRKICELYAKVLGSQEALYPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYGRVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREVLNALGKVAKKDIWVEEPESKDVPAIEITHTFLERNLPSVPGLLKITGVSTSVALLCFVLYKIKKLPC
  
Inhibitor
Name:
BDBM15613
Synonyms:
4-chloro-N-(2-morpholin-4-ylethyl)benzamide | 4-chloro-N-[2-(morpholin-4-yl)ethyl]benzamide | Aurorix | CHEMBL86304 | MCL | Moclobemide
Type:
Small organic molecule
Emp. Form.:
C13H17ClN2O2
Mol. Mass.:
268.739
SMILES:
Clc1ccc(cc1)C(=O)NCCN1CCOCC1
Structure:
Search PDB for entries with ligand similarity: