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Target
Fatty acid-binding protein, adipocyte
Ligand
BDBM50319698
Substrate
n/a
Meas. Tech.
ChEMBL_634822 (CHEMBL1120072)
IC50
59500±n/a nM
Citation
 Cai, H; Yan, G; Zhang, X; Gorbenko, O; Wang, H; Zhu, W Discovery of highly selective inhibitors of human fatty acid binding protein 4 (FABP4) by virtual screening. Bioorg Med Chem Lett 20:3675-9 (2010) [PubMed]  Article 
Target
Name:
Fatty acid-binding protein, adipocyte
Synonyms:
A-FABP | AFABP | ALBP | Adipocyte lipid-binding protein | FABP4 | FABP4_HUMAN | Fatty acid binding protein adipocyte | Fatty acid-binding protein 4 | Fatty acid-binding protein 4 (FABP4)
Type:
Enzyme
Mol. Mass.:
14719.23
Organism:
Homo sapiens (Human)
Description:
P15090
Residue:
132
Sequence:
MCDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNMIISVNGDVITIKSESTFKNTEISFILGQEFDEVTADDRKVKSTITLDGGVLVHVQKWDGKSTTIKRKREDDKLVVECVMKGVTSTRVYERA
  
Inhibitor
Name:
BDBM50319698
Synonyms:
2-(2-(3-chloro-4-fluorophenylamino)-2-oxoethylthio)acetic acid | CHEMBL1086224
Type:
Small organic molecule
Emp. Form.:
C10H9ClFNO3S
Mol. Mass.:
277.7
SMILES:
OC(=O)CSCC(=O)Nc1ccc(F)c(Cl)c1
Structure:
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