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Target
Estrogen receptor beta
Ligand
BDBM50320308
Substrate
n/a
Meas. Tech.
ChEMBL_635745 (CHEMBL1120284)
IC50
41700±n/a nM
Citation
 Lee, da Y; Kim, do H; Lee, HJ; Lee, Y; Ryu, KH; Jung, BI; Song, YS; Ryu, JH New estrogenic compounds isolated from Broussonetia kazinoki. Bioorg Med Chem Lett 20:3764-7 (2010) [PubMed]  Article 
Target
Name:
Estrogen receptor beta
Synonyms:
ER-beta | ESR2 | ESR2_HUMAN | ESTRB | Estradiol receptor beta (ERβ) | Estrogen receptor | Estrogen receptor (ER beta) | Estrogen receptor beta | Estrogen receptor beta (ER beta) | Estrogen receptor beta (ER) | NR3A2 | Nuclear receptor subfamily 3 group A member 2 | estrogen beta
Type:
Protein
Mol. Mass.:
59238.43
Organism:
Homo sapiens (Human)
Description:
Q92731
Residue:
530
Sequence:
MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPSNVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVNRETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHVLRGCKSSITGSECSPAEDSKSKEGSQNPQSQ
  
Inhibitor
Name:
BDBM50320308
Synonyms:
CHEMBL1084746 | kazinol U
Type:
Small organic molecule
Emp. Form.:
C20H22O4
Mol. Mass.:
326.3863
SMILES:
[#6]\[#6](-[#6])=[#6]\[#6]-c1c(-[#8])c(-[#8])ccc1-[#6@H]-1-[#6]-[#6]-c2ccc(-[#8])cc2-[#8]-1 |r|
Structure:
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