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Target
High affinity choline transporter 1
Ligand
BDBM50416496
Substrate
n/a
Meas. Tech.
ChEMBL_644789 (CHEMBL1211032)
Ki
210377.84±n/a nM
Citation
 Geldenhuys, WJ; Allen, DD; Lockman, PR 3-D-QSAR and docking studies on the neuronal choline transporter. Bioorg Med Chem Lett 20:4870-7 (2010) [PubMed]  Article 
Target
Name:
High affinity choline transporter 1
Synonyms:
Choline transporter | Cht1 | SC5A7_MOUSE | Slc5a7
Type:
PROTEIN
Mol. Mass.:
63358.06
Organism:
Mus musculus
Description:
ChEMBL_644789
Residue:
580
Sequence:
MSFHVEGLVAIILFYLLIFLVGIWAAWKTKNSGNPEERSEAIIVGGRDIGLLVGGFTMTATWVGGGYINGTAEAVYGPGCGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQIYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIIDVDVNISVIVSALIAILYTLVGGLYSVAYTDVVQLFCIFIGLWISVPFALSHPAVTDIGFTAVHAKYQSPWLGTIESVEVYTWLDNFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMALPAICIGAIGASTDWNQTAYGYPDPKTKEEADMILPIVLQYLCPVYISFFGLGAVSAAVMSSADSSILSASSMFARNIYQLSFRQNASDKEIVWVMRITVLVFGASATAMALLTKTVYGLWYLSSDLVYIIIFPQLLCVLFIKGTNTYGAVAGYIFGLFLRITGGEPYLYLQPLIFYPGYYSDKNGIYNQRFPFKTLSMVTSFFTNICVSYLAKYLFESGTLPPKLDVFDAVVARHSEENMDKTILVRNENIKLNELAPVKPRQSLTLSSTFTNKEALLDVDSSPEGSGTEDNLQ
  
Inhibitor
Name:
BDBM50416496
Synonyms:
CHEMBL1209650
Type:
Small organic molecule
Emp. Form.:
C9H18NO
Mol. Mass.:
156.2448
SMILES:
CC1C(O)C2CC[N+]1(C)CC2 |TLB:0:1:6.5:9.10,THB:3:2:6.5:9.10,(7.89,-10.07,;8.66,-8.7,;8.46,-7.29,;7.09,-6.52,;9.96,-6.64,;11.34,-7.26,;11.62,-8.68,;10.22,-8.03,;10.17,-9.6,;10.49,-6.09,;10.03,-4.96,)|
Structure:
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