Reaction Details Report a problem with these data
Target
Delta-type opioid receptor
Ligand
BDBM50324023
Substrate
n/a
Meas. Tech.
ChEMBL_647236 (CHEMBL1217377)
IC50
0.32±n/a nM
Citation
 Balboni, G; Marzola, E; Sasaki, Y; Ambo, A; Marczak, ED; Lazarus, LH; Salvadori, S Role of 2',6'-dimethyl-l-tyrosine (Dmt) in some opioid lead compounds. Bioorg Med Chem 18:6024-30 (2010) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
DOR-1 | K56 | MSL-2 | OPIATE Delta | OPRD_MOUSE | Opioid receptors; mu and delta | Oprd1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40577.25
Organism:
MOUSE
Description:
P32300
Residue:
372
Sequence:
MELVPSARAELQSSPLVNLSDAFPSAFPSAGANASGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTQPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRTPCGRQEPGSLRRPRQATTRERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50324023
Synonyms:
(2S,5S,8R,11S,14S)-2-amino-14-((S)-1-((S)-1-(2-amino-2-oxoethylamino)-3-methyl-1-oxobutan-2-ylamino)-3-methyl-1-oxobutan-2-ylcarbamoyl)-11-benzyl-1-(4-hydroxy-2,6-dimethylphenyl)-5-(4-hydroxybenzyl)-8-methyl-3,6,9,12-tetraoxo-4,7,10,13-tetraazaheptadecan-17-oic acid | CHEMBL1213989
Type:
Small organic molecule
Emp. Form.:
C49H67N9O12
Mol. Mass.:
974.1094
SMILES:
CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(C)C)C(=O)NCC(N)=O |r|
Structure:
Search PDB for entries with ligand similarity: