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Target
B1 bradykinin receptor
Ligand
BDBM50151891
Substrate
n/a
Meas. Tech.
ChEMBL_662800 (CHEMBL1252539)
Ki
7.7±n/a nM
Citation
 Huang, H; Player, MR Bradykinin B1 receptor antagonists as potential therapeutic agents for pain. J Med Chem 53:5383-99 (2010) [PubMed]  Article 
Target
Name:
B1 bradykinin receptor
Synonyms:
B1R | BDKRB1 | BK-1 receptor | BKRB1_MACMU
Type:
PROTEIN
Mol. Mass.:
40259.67
Organism:
Macaca mulatta
Description:
ChEMBL_662800
Residue:
352
Sequence:
MASWPPLELQSSNQSQLFPQNATACDNAPEAWDLLHRVLPTFIISICSFGLLGNLFVLLVFLLPRRRLNVAEIYLANLAASDLVFVLGLPFWAENIWNQFNWPFGALLCRVINGIIKANLFISIFLVVAISQDRYCVLVHPMASRRRQRRRQARVTCVLIWVVGGLLSIPTFLLRSIQAVPDLNITACILLLPHEAWHFARIVELNILAFLLPLAAIIFFNYHILASLRGREEVSRTRCGGSKDSKTTALILTLVVAFLVCWAPYHFFAFLEFLFQVQAVRGCFWEDFIDLGLQLANFLAFTNSSLNPVIYVFVGRLFRTKVWELYKQCTPKSLAPISSSHRKEIFQLFWRN
  
Inhibitor
Name:
BDBM50151891
Synonyms:
CHEMBL273869 | {2-(2,2-Diphenyl-ethylamino)-5-[4-(4-methyl-piperazine-1-carbonyl)-piperidine-1-sulfonyl]-phenyl}-morpholin-4-yl-methanone
Type:
Small organic molecule
Emp. Form.:
C36H45N5O5S
Mol. Mass.:
659.838
SMILES:
CN1CCN(CC1)C(=O)C1CCN(CC1)S(=O)(=O)c1ccc(NCC(c2ccccc2)c2ccccc2)c(c1)C(=O)N1CCOCC1
Structure:
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