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Target
Kappa-type opioid receptor
Ligand
BDBM50327508
Substrate
n/a
Meas. Tech.
ChEMBL_664644 (CHEMBL1260358)
Ki
>1000±n/a nM
Citation
 Lee, DY; Yang, L; Xu, W; Deng, G; Guo, L; Liu-Chen, LY Synthesis and biological evaluation of C-2 halogenated analogs of salvinorin A. Bioorg Med Chem Lett 20:5749-52 (2010) [PubMed]  Article 
Target
Name:
Kappa-type opioid receptor
Synonyms:
K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42648.76
Organism:
Homo sapiens (Human)
Description:
P41145
Residue:
380
Sequence:
MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRVRNTVQDPAYLRDIDGMNKPV
  
Inhibitor
Name:
BDBM50327508
Synonyms:
(2R,3aS,6aS,7R,9R)-9-Bromo-2-furan-3-yl-3a,6a-dimethyl-2,3,3a,4,5,6,6a,7,8,9-decahydro-benzo[de]chromene-4,7-dicarboxylic acid 7-methyl este r | CHEMBL1257730
Type:
Small organic molecule
Emp. Form.:
C21H25BrO6
Mol. Mass.:
453.324
SMILES:
COC(=O)[C@@H]1C[C@@H](Br)C2=C3[C@@]1(C)CCC(C(O)=O)[C@]3(C)C[C@@H](O2)c1ccoc1 |r,c:8|
Structure:
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