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Target
Beta-lactamase
Ligand
BDBM50021959
Substrate
n/a
Meas. Tech.
ChEMBL_667853 (CHEMBL1263491)
IC50
20±n/a nM
Citation
 Mendonça, N; Manageiro, V; Bonnet, R; Caniça, M Biochemical characterization of SHV-55, an extended-spectrum class A beta-lactamase from Klebsiella pneumoniae. Antimicrob Agents Chemother 52:1897-8 (2008) [PubMed]  Article 
Target
Name:
Beta-lactamase
Synonyms:
Beta-lactamase SHV-55 | Extended-spectrum beta-lactamase SHV-55
Type:
PROTEIN
Mol. Mass.:
31241.78
Organism:
Klebsiella pneumoniae
Description:
ChEMBL_667853
Residue:
286
Sequence:
MRFIRLCIISLLATLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHWQR
  
Inhibitor
Name:
BDBM50021959
Synonyms:
CHEMBL777 | MM 14151 | US9120808, Clavulanic acid potassium salt | antibiotic MM 14151 | clavulanic acid
Type:
Small organic molecule
Emp. Form.:
C8H9NO5
Mol. Mass.:
199.1608
SMILES:
OC\C=C1/O[C@@H]2CC(=O)N2[C@H]1C(O)=O |r|
Structure:
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