Reaction Details Report a problem with these data
Target
Sortase family protein
Ligand
BDBM50331607
Substrate
n/a
Meas. Tech.
ChEMBL_687441 (CHEMBL1292117)
IC50
115000±n/a nM
Citation
 Lee, YJ; Han, YR; Park, W; Nam, SH; Oh, KB; Lee, HS Synthetic analogs of indole-containing natural products as inhibitors of sortase A and isocitrate lyase. Bioorg Med Chem Lett 20:6882-5 (2010) [PubMed]  Article 
Target
Name:
Sortase family protein
Synonyms:
Sortase | Sortase A (SrtA)
Type:
Enzyme
Mol. Mass.:
23546.15
Organism:
Staphylococcus aureus
Description:
n/a
Residue:
206
Sequence:
MKKWTNRLMTIAGVVLILVAAYLFAKPHIDNYLHDKDKDEKIEQYDKNVKEQASKDKKQQAKPQIPKDKSKVAGYIEIPDADIKEPVYPGPATPEQLNRGVSFAEENESLDDQNISIAGHTFIDRPNYQFTNLKAAKKGSMVYFKVGNETRKYKMTSIRDVKPTDVGVLDEQKGKDKQLTLITCDDYNEKTGVWEKRKIFVATEVK
  
Inhibitor
Name:
BDBM50331607
Synonyms:
6-methoxy-1-phenyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole | CHEMBL1289751
Type:
Small organic molecule
Emp. Form.:
C18H18N2O
Mol. Mass.:
278.3483
SMILES:
COc1ccc2[nH]c3C(NCCc3c2c1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: