Reaction Details Report a problem with these data
Target
Ribonuclease pancreatic
Ligand
BDBM50331792
Substrate
n/a
Meas. Tech.
ChEMBL_686759 (CHEMBL1290998)
Ki
193000±n/a nM
Citation
 Debnath, J; Dasgupta, S; Pathak, T Comparative inhibitory activity of 3'- and 5'-functionalized nucleosides on ribonuclease A. Bioorg Med Chem 18:8257-63 (2010) [PubMed]  Article 
Target
Name:
Ribonuclease pancreatic
Synonyms:
CAM-RNase A | RNAS1_BOVIN | RNASE1 | RNAse A | RNS1
Type:
Enzyme
Mol. Mass.:
16468.79
Organism:
Bison bison (American bison)
Description:
carboxamidomethylated RNase A
Residue:
150
Sequence:
MALKSLVLLSLLVLVLLLVRVQPSLGKETAAAKFERQHMDSSTSAASSSNYCNQMMKSRNLTKDRCKPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPNCAYKTTQANKHIIVACEGNPYVPVHFDASV
  
Inhibitor
Name:
BDBM50331792
Synonyms:
5'-Carboxy thymidine | CHEMBL1288589
Type:
Small organic molecule
Emp. Form.:
C10H12N2O6
Mol. Mass.:
256.2121
SMILES:
Cc1cn([C@H]2C[C@H](O)[C@H](O2)C(O)=O)c(=O)[nH]c1=O |r|
Structure:
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