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Target
Metallo-beta-lactamase VIM-2
Ligand
BDBM50336508
Substrate
n/a
Meas. Tech.
ChEMBL_723554 (CHEMBL1676794)
Ki
120000±n/a nM
Citation
 Ishii, Y; Eto, M; Mano, Y; Tateda, K; Yamaguchi, K In vitro potentiation of carbapenems with ME1071, a novel metallo-beta-lactamase inhibitor, against metallo-beta-lactamase- producing Pseudomonas aeruginosa clinical isolates. Antimicrob Agents Chemother 54:3625-9 (2010) [PubMed]  Article 
Target
Name:
Metallo-beta-lactamase VIM-2
Synonyms:
Beta-lactamase VIM-2 | Metallo-beta-lactamase VIM-2 (VIM-2)
Type:
Protein
Mol. Mass.:
28318.00
Organism:
Pseudomonas aeruginosa (g-Proteobacteria)
Description:
n/a
Residue:
266
Sequence:
MFKLLSKLLVYLTASIMAIASPLAFSVDSSGEYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNRSVVE
  
Inhibitor
Name:
BDBM50336508
Synonyms:
CHEMBL1673299 | sodium 2,3-diethylmaleate
Type:
Small organic molecule
Emp. Form.:
C8H10O4
Mol. Mass.:
170.1637
SMILES:
CC\C(C([O-])=O)=C(/CC)C([O-])=O
Structure:
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