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Target
Neuropeptide Y receptor type 1
Ligand
BDBM50343740
Substrate
n/a
Meas. Tech.
ChEMBL_747562 (CHEMBL1777096)
Ki
50±n/a nM
Citation
 Keller, M; Erdmann, D; Pop, N; Pluym, N; Teng, S; Bernhardt, G; Buschauer, A Red-fluorescent argininamide-type NPY Y1 receptor antagonists as pharmacological tools. Bioorg Med Chem 19:2859-78 (2011) [PubMed]  Article 
Target
Name:
Neuropeptide Y receptor type 1
Synonyms:
NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44399.07
Organism:
Homo sapiens (Human)
Description:
NPY-Y1 NPY1R HUMAN::P25929
Residue:
384
Sequence:
MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEKI
  
Inhibitor
Name:
BDBM50343740
Synonyms:
1-(6-(Amino((R)-4-(2,2-diphenylacetamido)-5-(4-hydroxybenzylamino)-5-oxopentylamino)methyleneamino)-6-oxohexyl)-4-((1E,3E)-4-(4-(dimethylamino)phenyl)buta-1,3-dienyl)-2,6-dimethylpyridinium-hydrotrifluoroacetate | CHEMBL1774216
Type:
Small organic molecule
Emp. Form.:
C52H62N7O4
Mol. Mass.:
849.0926
SMILES:
CN(C)c1ccc(\C=C\C=Cc2cc(C)[n+](CCCCCC(=O)NC(N)=NCCC[C@@H](NC(=O)C(c3ccccc3)c3ccccc3)C(=O)NCc3ccc(O)cc3)c(C)c2)cc1 |r,w:26.26,10.10|
Structure:
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