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Target
Neuropeptide Y receptor type 5
Ligand
BDBM50343728
Substrate
n/a
Meas. Tech.
ChEMBL_747566 (CHEMBL1777100)
Ki
>400±n/a nM
Citation
 Keller, M; Erdmann, D; Pop, N; Pluym, N; Teng, S; Bernhardt, G; Buschauer, A Red-fluorescent argininamide-type NPY Y1 receptor antagonists as pharmacological tools. Bioorg Med Chem 19:2859-78 (2011) [PubMed]  Article 
Target
Name:
Neuropeptide Y receptor type 5
Synonyms:
NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor
Type:
Enzyme
Mol. Mass.:
50746.64
Organism:
Homo sapiens (Human)
Description:
Q15761
Residue:
445
Sequence:
MDLELDEYYNKTLATENNTAATRNSDFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNLLILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSLVELQETFGSALLSSRYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGLSNKENRLEENEMINLTLHPSKKSGPQVKLSGSHKWSYSFIKKHRRRYSKKTACVLPAPERPSQENHSRILPENFGSVRSQLSSSSKFIPGVPTCFEIKPEENSDVHELRVKRSVTRIKKRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLVSLIHCLHM
  
Inhibitor
Name:
BDBM50343728
Synonyms:
3-((R)-9-Amino-4-(2,2-diphenylacetamido)-1-(4-hydroxyphenyl)-3,11,18-trioxo-2,8,10,12,17-pentaazahenicos-9-en-21-yl)-2-((1E,3E)-4-(4-(dimethylamino)phenyl)buta-1,3-enyl)benzo[d]thiazol-3-ium hydrotrifluoroacetate | CHEMBL1774344
Type:
Small organic molecule
Emp. Form.:
C55H64N9O5S
Mol. Mass.:
963.218
SMILES:
CN(C)c1ccc(C=CC=Cc2sc3ccccc3[n+]2CCCC(=O)NCCCCNC(=O)NC(N)=NCCC[C@@H](NC(=O)C(c2ccccc2)c2ccccc2)C(=O)NCc2ccc(O)cc2)cc1 |r,w:8.8,36.38,10.10|
Structure:
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