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Target
Retinol-binding protein 4
Ligand
BDBM50347594
Substrate
n/a
Meas. Tech.
ChEMBL_756077 (CHEMBL1804187)
EC50
1260±n/a nM
Citation
 Campos-Sandoval, JA; Redondo, C; Kinsella, GK; Pal, A; Jones, G; Eyre, GS; Hirst, SC; Findlay, JB Fenretinide derivatives act as disrupters of interactions of serum retinol binding protein (sRBP) with transthyretin and the sRBP receptor. J Med Chem 54:4378-87 (2011) [PubMed]  Article 
Target
Name:
Retinol-binding protein 4
Synonyms:
PRBP | Plasma retinol-binding protein | RBP | RBP4 | RET4_HUMAN | Retinol-binding protein 4 | Retinol-binding protein 4 (RBP4) | spa binding assay for rbp4
Type:
Protein
Mol. Mass.:
23008.75
Organism:
Homo sapiens (Human)
Description:
P02753
Residue:
201
Sequence:
MKWVWALLLLAALGSGRAERDCRVSSFRVKENFDKARFSGTWYAMAKKDPEGLFLQDNIVAEFSVDETGQMSATAKGRVRLLNNWDVCADMVGTFTDTEDPAKFKMKYWGVASFLQKGNDDHWIVDTDYDTYAVQYSCRLLNLDGTCADSYSFVFSRDPNGLPPEAQKIVRQRQEELCLARQYRLIVHNGYCDGRSERNLL
  
Inhibitor
Name:
BDBM50347594
Synonyms:
CHEMBL1801542
Type:
Small organic molecule
Emp. Form.:
C29H37NO4
Mol. Mass.:
463.6084
SMILES:
COC(=O)COc1ccc(NC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C2=C(C)CCCC2(C)C)cc1 |c:23|
Structure:
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