Reaction Details Report a problem with these data
Target
Prostaglandin D2 receptor
Ligand
BDBM50350365
Substrate
n/a
Meas. Tech.
ChEMBL_761111 (CHEMBL1815365)
Ki
22±n/a nM
Citation
 Iwahashi, M; Shimabukuro, A; Onoda, T; Matsunaga, Y; Okada, Y; Matsumoto, R; Nambu, F; Nakai, H; Toda, M Discovery of selective indole-based prostaglandin D2 receptor antagonist. Bioorg Med Chem 19:4574-88 (2011) [PubMed]  Article 
Target
Name:
Prostaglandin D2 receptor
Synonyms:
PD2R_MOUSE | Prostanoid DP receptor | Ptgdr
Type:
PROTEIN
Mol. Mass.:
40018.63
Organism:
Mus musculus
Description:
ChEMBL_788408
Residue:
357
Sequence:
MNESYRCQTSTWVERGSSATMGAVLFGAGLLGNLLALVLLARSGLGSCRPGPLHPPPSVFYVLVCGLTVTDLLGKCLISPMVLAAYAQNQSLKELLPASGNQLCETFAFLMSFFGLASTLQLLAMAVECWLSLGHPFFYQRHVTLRRGVLVAPVVAAFCLAFCALPFAGFGKFVQYCPGTWCFIQMIHKERSFSVIGFSVLYSSLMALLVLATVVCNLGAMYNLYDMHRRQRHYPHRCSRDRAQSGSDYRHGSLHPLEELDHFVLLALMTVLFTMCSLPLIYRAYYGAFKLENKAEGDSEDLQALRFLSVISIVDPWIFIIFRTSVFRMLFHKVFTRPLIYRNWSSHSQQSNVESTL
  
Inhibitor
Name:
BDBM50350365
Synonyms:
CHEMBL1813288
Type:
Small organic molecule
Emp. Form.:
C30H30N2O4
Mol. Mass.:
482.5702
SMILES:
CCN1C(COc2ccc(C(=O)n3c(C)c(CC(O)=O)c4ccccc34)c(C)c2)Cc2ccccc12
Structure:
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