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Target
Prostaglandin D2 receptor
Ligand
BDBM50350370
Substrate
n/a
Meas. Tech.
ChEMBL_761111 (CHEMBL1815365)
Ki
9.9±n/a nM
Citation
 Iwahashi, M; Shimabukuro, A; Onoda, T; Matsunaga, Y; Okada, Y; Matsumoto, R; Nambu, F; Nakai, H; Toda, M Discovery of selective indole-based prostaglandin D2 receptor antagonist. Bioorg Med Chem 19:4574-88 (2011) [PubMed]  Article 
Target
Name:
Prostaglandin D2 receptor
Synonyms:
PD2R_MOUSE | Prostanoid DP receptor | Ptgdr
Type:
PROTEIN
Mol. Mass.:
40018.63
Organism:
Mus musculus
Description:
ChEMBL_788408
Residue:
357
Sequence:
MNESYRCQTSTWVERGSSATMGAVLFGAGLLGNLLALVLLARSGLGSCRPGPLHPPPSVFYVLVCGLTVTDLLGKCLISPMVLAAYAQNQSLKELLPASGNQLCETFAFLMSFFGLASTLQLLAMAVECWLSLGHPFFYQRHVTLRRGVLVAPVVAAFCLAFCALPFAGFGKFVQYCPGTWCFIQMIHKERSFSVIGFSVLYSSLMALLVLATVVCNLGAMYNLYDMHRRQRHYPHRCSRDRAQSGSDYRHGSLHPLEELDHFVLLALMTVLFTMCSLPLIYRAYYGAFKLENKAEGDSEDLQALRFLSVISIVDPWIFIIFRTSVFRMLFHKVFTRPLIYRNWSSHSQQSNVESTL
  
Inhibitor
Name:
BDBM50350370
Synonyms:
CHEMBL1813119
Type:
Small organic molecule
Emp. Form.:
C29H28N2O6
Mol. Mass.:
500.5424
SMILES:
COc1ccc2n(C(=O)c3ccc(OC[C@@H]4CN(C)c5ccccc5O4)cc3)c(C)c(CC(O)=O)c2c1 |r|
Structure:
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